Box of Champix tablets used to help quit smoking

Champix (Varenicline)

Price range: £29.99 through £64.99

Champix (Varenicline) Tablets are prescription-only medication that assists adults in quitting smoking by reducing cravings and withdrawal symptoms through partial stimulation of nicotine receptors in the brain.
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Description

Champix (varenicline tartrate) is a prescription medicine designed to support smoking cessation in adults. It is part of a structured 12-week programme that helps reduce nicotine withdrawal symptoms and cravings, making it easier to quit smoking successfully. Champix is often used by individuals who have struggled to stop smoking using other methods such as patches, gum, or willpower alone.

How It Works
The active ingredient in Champix, varenicline, is a partial agonist of the α4β2 nicotinic acetylcholine receptors in the brain. It works in two key ways: by mildly stimulating the receptor to reduce cravings and withdrawal symptoms, and by blocking nicotine from binding to these receptors if the person smokes. This dual action both reduces the satisfaction derived from smoking and supports a gradual transition away from nicotine dependence.

Why Choose Champix
Champix is one of the most effective prescription treatments for smoking cessation, with clinical trials showing higher quit success rates compared to nicotine replacement therapies alone. Its structured dosage schedule helps ease users into the treatment and supports long-term abstinence. Unlike nicotine-based options, Champix does not contain nicotine, and its effects persist even if the individual smokes during the early weeks of treatment.

Important Note
Champix must be used exactly as prescribed. It should not be taken by those with a history of suicidal thoughts or severe psychiatric illness unless carefully monitored. Some users experience vivid dreams, mood changes, or nausea. Alcohol intake may worsen side effects. A doctor should determine suitability, especially in people with kidney issues or those on multiple medications. Regular follow-up and support significantly improve success rates.

Directions

Please refer to the medication’s patient information leaflet before starting any new medication.

  • Start Champix one week before your planned quit date

  • Week 1: Take 0.5 mg once daily for 3 days, then twice daily for 4 days

  • Week 2–12: Take 1 mg twice daily

  • Swallow whole with water, with or without food

  • Do not exceed the prescribed dose

  • Store below 25°C

  • Keep in original packaging

  • Keep out of reach of children

Ingredients

Active Ingredient:

  • Varenicline tartrate (0.5 mg or 1 mg tablets)

Other Ingredients:

  • Cellulose

  • Calcium hydrogen phosphate

  • Silica colloidal anhydrous

  • Magnesium stearate

  • Titanium dioxide

  • Indigo carmine

  • Hypromellose

Side Effects

Common side effects may include:

  • Nausea

  • Headache

  • Vivid dreams

  • Insomnia

  • Flatulence

Serious (rare) side effects:

  • Mood changes or depression

  • Suicidal thoughts or behaviour

  • Seizures

  • Allergic reaction

Stop the medicine and seek medical attention if serious side effects occur.

Warnings

Do not take Champix if allergic to varenicline or any listed ingredients. Caution is advised in individuals with a history of mental health conditions or seizures. Not suitable for pregnant or breastfeeding women unless advised by a doctor. Monitor mood and behaviour closely during use, especially if psychiatric history is present. Avoid excessive alcohol as it may heighten side effects.

  • Yes, it's common to continue smoking during the first week of treatment. Aim to stop smoking on your quit date, which should be set within the first 1–2 weeks of starting Champix.

  • Champix works by partially stimulating nicotine receptors in the brain, reducing cravings and withdrawal symptoms while also decreasing the satisfaction derived from smoking.

  • Champix is intended for adults over 18 years of age. It's not recommended for use in children or adolescents. Consult your doctor to determine if it's appropriate for you.

  • If you miss a dose, take it as soon as you remember. If it's close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • You should begin taking Champix 1–2 weeks before your planned quit date to allow the medication to build up in your system.