Maloff Protect 250 mg / 100 mg Tablets

Price range: £59.99 through £84.99

Maloff Protect is a pharmacy medicine for adult malaria prevention, containing atovaquone and proguanil.
OTC alternative to Malarone – trusted, daily dosing for safe travel.
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Description

Maloff Protect is an over-the-counter malaria prevention medicine for adults aged 18 and over. It contains the same active ingredients and strength as Malarone: Atovaquone 250mg and Proguanil Hydrochloride 100mg.

Malaria is a life-threatening disease caused by mosquito-borne parasites, particularly dangerous in parts of Africa, Asia, and South America. Maloff Protect is designed for travellers heading to areas where Plasmodium falciparum, the most severe type of malaria, is prevalent.

How It Works

Maloff Protect contains two active substances that work in combination to stop malaria parasites from multiplying in the bloodstream:

Atovaquone disrupts parasite energy production by targeting mitochondrial electron transport.

Proguanil inhibits DNA replication by blocking the folate synthesis pathway.

This dual action kills the malaria parasite at an early stage of its lifecycle, providing reliable protection.

Why Choose Maloff Protect

Maloff Protect is a convenient alternative to prescription antimalarials and is available without a doctor’s prescription in the UK. It is recommended for travellers seeking short-term malaria protection.

Key benefits:

Same ingredients and dosage as Malarone

Available without prescription

Convenient once-daily dosing

Effective against chloroquine-resistant malaria

Short post-travel treatment (7 days)

It is suitable for last-minute travel preparations and trusted by pharmacists for its proven efficacy.

Important Note

This medication should not be used in children or individuals under 40kg. Always consult the pharmacist to ensure suitability. Begin treatment 1–2 days before travel, continue daily during the trip, and for 7 days after leaving the risk area.

Directions

Note: Always follow pharmacist guidance and package leaflet instructions.

  • Dosage for Adults (18+ and >40kg):

    • One tablet once daily

  • Schedule:

    • Start 1–2 days before travel

    • Take daily during travel

    • Continue for 7 days after leaving malaria zone

  • Administration:

    • Take with food or milk

    • Swallow whole with water

Storage:

  • Store below 30°C

  • Keep out of reach of children

  • Do not use after expiry date

Ingredients

  • Active Ingredients:

    • Atovaquone 250mg

    • Proguanil hydrochloride 100mg

  • Key Excipients:

    • Lactose monohydrate

    • Cellulose

    • Povidone

    • Sodium starch glycolate

Side Effects

  • Common side effects:

    • Nausea

    • Headache

    • Diarrhoea

    • Abdominal discomfort

    Rare but serious effects:

    • Rash or allergic reaction

    • Mouth ulcers

    • Unusual dreams or hallucinations

    Discontinue use and seek medical advice for severe reactions.

Warnings

  • Contraindications:

    • Allergy to atovaquone or proguanil

    • Severe kidney impairment

  • Pregnancy/Breastfeeding:

    • Not recommended without medical supervision

  • Drug Interactions:

    • Avoid with rifampicin, tetracycline, metoclopramide, or warfarin unless advised

  • Age Restrictions:

    • Not suitable for under 18s or under 40kg

  • Yes, it should be taken with food or a milky drink to improve absorption and reduce the chance of nausea.
  • No, Maloff Protect is a Pharmacy (P) Medicine, available following a pharmacist-led consultation.
  • Maloff Protect begins working within 1–2 days of starting the course. Start treatment at least 1–2 days before entering a malaria-risk area.
  • It is typically used for short-term travel up to 28 days. Longer use should be supervised by a GP.
  • Maloff Protect is used to prevent malaria in adults travelling to areas where Plasmodium falciparum is common.